ASU scientists develop unique software for predicting pulmonary thromboembolism

3 July 2018 Department of Information and Media Communications
The scientists of Altai State University are currently working on a computer program with the help of which it will be possible to predict the development of one of the most common cardiovascular pathologies – pulmonary thromboembolism.

The project team includes its leader, Assistant Professor of the Department of Computer Technology and Electronics, Candidate of Technical Sciences Alexander A. Shaidurov, as well as researchers and lecturers of the Faculty of Physics and Technology and medical workers.

The scientists will for the first time study the risk of venous thrombus and the danger of its embolism on the basis of the generally accepted and generally available laboratory and instrumental techniques using modern methods of statistical data processing combined with mathematical modeling of disease processes.

Using the method for mathematical modeling of phlebothrombosis and thrombus flotation processes developed within the framework of the project, a method will be developed to assess the risks of the need for thrombolytic therapy. In contrast to the world medical practice, it is proposed to use available clinical, laboratory and instrumental data to identify the risk of phlebothrombosis and pulmonary embolism.

"The methods for diagnosing the thrombotic process and its embolic complications available in clinical practice presuppose the use of specific methods for examination that are not available in all medical institutions because of the high cost of equipment and supplies, and because of the high requirements for the personnel qualification," Alexander A. Shaidurov explains. “This state of affairs makes it difficult to diagnose the pathological process early and results in the fact that treatment begins in the late stages of the disease and rarely leads to complete cure. In this connection, diagnostic methods based on the results of available clinical trials are of interest, which would allow detecting individuals at risk of thrombotic development and its embolic complications at early stages of the development of the pathological. The implementation of this project should solve this problem."

The project will result in the development of screening computer programs that will be available to the medical specialists of the primary level for their work to identify the predisposition toward the disease indicated in the project and its detection in the early stages. In addition, the scientists plan to distribute the developed programs through social networks with access through personal mobile gadgets, which will ensure global coverage of various social groups, including socially disadvantaged groups.

According to the developers, the social significance of the project is to increase the effectiveness of medical care by early detection and prevention of cardiovascular diseases. This approach will help raise the prime working years and life expectancy of the population and reduce premature mortality.

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